How post-translational modifications impact protein dynamics and stability—experimental and theoretical investigations

Yuhao Li, Hailong Chen, Chun Tang,*(2025),SCIENTIA SINICA Chimica. https://doi.org/10.1360/SSC-2025-0016

Learn more

Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration

Cong Chen,Tong-Yao Gao,Hua-Wei Yi,Yi Zhang,Tong Wang,Zhi-Lin Lou,Tao-Feng Wei,Yun-Bi Lu,Ting-Ting Li,Chun Tang,Wei-Ping Zhang,(2025),eLife.https://doi.org/10.7554/eLife.103945.1

Learn more

Coarse-Grained Simulation Study of the Association of Selected Dipeptides

Mateusz Lesniewski, Emilia Iłowska, Justyna Sawicka, Zihan Li, Chun Tang, and Adam Liwo,(2024), J. Phys. Chem. B 128, 12403−12415. https://doi.org/10.1021/acs.jpcb.4c06305

Learn more

Dissecting diazirine photo-reaction mechanism for protein residue-specific cross-linking and distance mapping

Yida Jiang, Xinghe Zhang, Honggang Nie, Jianxiong Fan, Shuangshuang Di, Hui Fu, Xiu Zhang, Lijuan Wang, Chun Tang, (2024), Nat Commun 15(1), 6060 . https://doi.org/10.1038/s41467-024-50315-y

Learn more

Novel Vibrational Proteins

Yage Chen,Zhiliang Huang,Erli Cai,Shuchen Zhong,Haozheng Li,Wei Ju,Jie Yang,Wei Chen,Chun Tang,Ping Wang,(2024),Analytical Chemistry. DOI: 10.1021/acs.analchem.4c01569

Learn more

Connecting Protein Millisecond Conformational Dynamics to Protein Thermal Stability

Xue-Ni Hou, Bin Song, Chang Zhao, Wen-Ting Chu, Mei-Xia Ruan, Xu Dong, Ling-Shen Meng, Zhou Gong, Yu-Xiang Weng, Jie Zheng*, Jin Wang*, Chun Tang*, (2024), JACS Au. https://doi.org/10.1021/jacsau.4c00649

Learn more

Spatially resolved profiling of protein conformation and interactions by biocompatible chemical cross-linking in living cells

Lili Zhao, Yuxin An, Nan Zhao, Hang Gao, Weijie Zhang, Zhou Gong, Xiaolong Liu, Baofeng Zhao, Zhen Liang, Chun Tang, Lihua Zhang, Yukui Zhang ,Qun Zhao ,(2024),Nature Communications. DOI: 10.1038/s41467-024-52558-1

Learn more

ATP promotes protein coacervation through conformational compaction

Yueling Zhu, Shiyan Lin, Lingshen Meng, Min Sun, Maili Liu, Jingyuan Li, Chun Tang, Zhou Gong（2024）， Journal of Molecular Cell Biology, mjae038, https://doi.org/10.1093/jmcb/mjae038

Learn more

Assessment of Two Restraint Potentials for Coarse-Grained Chemical-Cross-Link-Assisted Modeling of Protein Structures

Mateusz Leśniewski, Maciej Pyrka, Cezary Czaplewski, Nguyen Truong Co, Yida Jiang, Zhou Gong, Chun Tang, Adam Liwo, (2024), J.Chem.Inf.Model.64,4,13771393.  https://doi.org/10.1021/acs.jcim.3c01890.

Learn more